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Chickenpox in adults - clinical management
A J Tunbridge1, J Breuer, K J M Jeffery
1Department of Infection and Tropical Medicine, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK. anne.tunbridge@sth.nhs.uk
Chickenpox (varicella zoster virus infection) is a growing concern for adults and immunocompromised individuals. Early antiviral therapy and vaccination are key to managing and preventing severe illness.
Area of Science:
- Infectious Diseases
- Immunology
- Public Health
Background:
- Varicella zoster virus (VZV) infection, or chickenpox, is often underestimated as a mild childhood illness.
- Chickenpox incidence is rising in adults and adolescents, posing a higher risk for severe outcomes, particularly in immunocompromised individuals.
Purpose of the Study:
- To review current best practices for managing adult chickenpox by UK specialist physicians.
- To provide guidance for emergency physicians and general practitioners on treatment and specialist care decisions.
Main Methods:
- Literature review of current VZV management strategies.
- Development of a clinical decision-making flowchart for healthcare providers.
Main Results:
- Antiviral therapy can alleviate symptoms and reduce severity if initiated early.
- Passive immunisation (varicella zoster immunoglobulin) is an option for high-risk exposed individuals.
- Active immunisation (vaccination) is available and widely implemented in many countries.
Conclusions:
- Prompt diagnosis and intervention are crucial for managing chickenpox in adults.
- A structured approach aids healthcare professionals in optimizing patient care and resource allocation.
- Vaccination remains a primary strategy for VZV prevention.
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