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Tsg101 can replace Nedd4 function in ASV Gag release but not membrane targeting.

Gisselle Medina1, Andrew Pincetic, Lorna S Ehrlich

  • 1Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA.

Virology
|June 17, 2008
PubMed
Summary

Avian sarcoma virus Gag protein release utilizes distinct pathways involving Nedd4 and Tsg101. Tsg101 can substitute for Nedd4 in viral budding, but through a different membrane-associated mechanism.

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