Association between raised blood pressure and dysglycemia in Hong Kong Chinese
Bernard M Y Cheung1, Nelson M S Wat, Annette W K Tso
1Department of Medicine, University of Hong Kong, Hong Kong, China. b.cheung@bham.ac.uk
Insights
Raised blood pressure and dysglycemia (diabetes or impaired glucose tolerance) share common risk factors and etiological pathways. Early screening and management for both conditions are recommended to prevent adverse cardiovascular events.
Area of Science:
- Cardiovascular disease research
- Metabolic syndrome studies
- Public health and epidemiology
Background:
- Hypertension and dysglycemia are significant global health concerns.
- Both conditions are linked to increased cardiovascular risk.
- Understanding their shared origins is crucial for effective prevention and treatment.
Purpose of the Study:
- To examine the relationship between elevated blood pressure and dysglycemia.
- To identify predictors for the onset of diabetes and hypertension.
Main Methods:
- Analysis of 1,862 subjects from the Hong Kong Cardiovascular Risk Factor Prevalence Study.
- Determination of factors predicting new-onset diabetes and hypertension in 1,496 individuals without these conditions at baseline.
Main Results:
- Diabetes and hypertension were associated with age, obesity, blood pressure, glucose levels, HDL cholesterol, and triglycerides.
- 58% of individuals with diabetes had elevated blood pressure; 56% with hypertension had dysglycemia.
- BMI, 2-h glucose, and systolic blood pressure independently predicted the development of diabetes, hypertension, or both.
Conclusions:
- Diabetes and hypertension share common etiological factors.
- Screening and management for precursor conditions are advised for patients with either diabetes or hypertension.
- Integrated management strategies may improve cardiovascular outcomes.
Objective:
To investigate the association between raised blood pressure and dysglycemia.
Research Design And Methods:
We studied the association between raised blood pressure and dysglycemia in 1,862 subjects in the Hong Kong Cardiovascular Risk Factor Prevalence Study cohort. We determined the factors predicting the development of diabetes and hypertension in 1,496 subjects who did not have either condition at baseline.
Results:
Diabetes and hypertension were both related to age, obesity indexes, blood pressure, glucose, HDL cholesterol, and triglycerides. Of subjects with diabetes, 58% had raised blood pressure. Of subjects with hypertension, 56% had dysglycemia. BMI and blood glucose 2 h after a 75-g oral glucose load were independent predictors of new-onset diabetes. Age, systolic blood pressure, and 2-h glucose were independent predictors of new-onset hypertension. BMI, systolic blood pressure, and 2-h glucose were independent predictors of the development of diabetes and hypertension together.
Conclusions:
Diabetes and hypertension share common etiological factors. Patients with diabetes or hypertension should be screened and managed for the precursor of the other condition.
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