Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Encephalitis and humoral immunity].

G Weippl, H Harasek, F Unger

    Padiatrie Und Padologie
    |January 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Quantitative value chain approaches for animal health and food safety.

    Food microbiology·2018
    Same author

    Imported reptiles as a risk factor for the global distribution of Escherichia coli harbouring the colistin resistance gene mcr-1.

    International journal of antimicrobial agents·2016
    Same author

    Sensitivity and Specificity Estimation for the Clinical Diagnosis of Highly Pathogenic Avian Influenza in the Egyptian Participatory Disease Surveillance Program.

    Avian diseases·2016
    Same author

    [Not Available].

    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2016
    Same author

    Nutritional marginal zinc deficiency disrupts placental 11β-hydroxysteroid dehydrogenase type 2 modulation.

    Food & function·2015
    Same author

    On dogs, people, and a rabies epidemic: results from a sociocultural study in Bali, Indonesia.

    Infectious diseases of poverty·2015

    Viral central nervous system infections in children can impair humoral immunity. Some patients exhibited selective antibody deficiencies, potentially linked to infection complications and elevated immunoglobulin M levels.

    Area of Science:

    • Pediatric Neurology
    • Immunology
    • Virology

    Background:

    • Viral infections of the central nervous system (CNS) can impact immune system function.
    • Humoral immunity plays a crucial role in defending against viral pathogens.
    • Understanding immune responses in pediatric CNS infections is vital for patient outcomes.

    Purpose of the Study:

    • To assess humoral immune function in children with viral CNS infections.
    • To investigate immunoglobulin levels and antibody titers in affected children.
    • To identify potential correlations between immune status and clinical complications.

    Main Methods:

    • Examined fourteen children diagnosed with viral CNS infections.
    • Measured serum concentrations of immune globulins (IgG, IgM).

    Related Experiment Videos

  • Determined antibody titers, including iso- and heteroagglutinins, and antibodies against diphtheria, pertussis, and tetanus. Tested antiviral antibodies based on infection history.

    • Main Results:

    • Selective antibody deficiency was identified in three children, two with elevated IgM levels.
    • These three children experienced complications during their infection.
    • Nine children presented with elevated serum IgM, with corresponding IgM-antibody titers in the high normal range or above.

    Conclusions:

    • Viral CNS infections can lead to diverse alterations in humoral immunity.
    • Selective antibody deficiencies may be associated with increased susceptibility to complications.
    • Elevated IgM levels are common in children with viral CNS infections, warranting further investigation.