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Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
Determination of risk factors for deep venous thrombosis in hospitalized children
Lan T Vu1, Kerilyn K Nobuhara, Hanmin Lee
1Division of Pediatric Surgery, Department of Surgery, University of California, Box 0570, San Francisco, CA 94143-0570, USA.
Insights
Deep venous thrombosis (DVT) in children has increased since 1997. Teenagers with underlying health conditions are most at risk for this condition.
Area of Science:
- Pediatric Medicine
- Vascular Health
- Epidemiology
Background:
- Deep venous thrombosis (DVT) is a serious condition that can affect children.
- Understanding trends and risk factors for pediatric DVT is crucial for effective prevention and treatment.
Purpose of the Study:
- To investigate the time trends in deep venous thrombosis (DVT) prevalence among pediatric inpatients.
- To identify risk factors associated with DVT in hospitalized children.
Main Methods:
- Cross-sectional study utilizing the Healthcare Cost and Utilization Project Kids' Inpatient Database (1997, 2000, 2003).
- Analysis included pediatric inpatients aged 1-17 years hospitalized for at least 4 days.
- Prevalence and adjusted prevalence ratios were calculated to assess trends and risk factors.
Main Results:
- The prevalence of DVT in pediatric inpatients was 4.2 per 1000 discharges.
- DVT prevalence significantly increased in 2000 and 2003 compared to 1997.
- Highest risk was observed in adolescents (15-17 years) with obesity, inflammatory bowel disease, hematologic malignancy, or specific surgical procedures.
Conclusions:
- A significant rise in the discharge diagnosis of lower extremity DVT has been observed since 1997.
- Teenagers with comorbid conditions represent a high-risk group for DVT.
- Further research into pediatric DVT prevention and management is warranted.
Purpose:
Our objective was to determine the time trend and risk factors for deep venous thrombosis (DVT) of the lower extremities among pediatric inpatients.
Methods:
This cross-sectional study used the data from the Health Care Cost and Utilization Project Kids' Inpatient Database for the years of 1997, 2000, and 2003 to estimate the DVT prevalence and crude and adjusted prevalence ratios. Patients between the ages of 1 and 17 years and who were hospitalized for at least 4 days were included.
Results:
The weighted prevalence of DVT was 4.2 per 1000 hospital discharges (95% confidence interval [CI], 3.4-3.7). Independent of age, the prevalence of DVT was significantly greater in 2000 and 2003 compared to 1997, prevalence ratio (PR) of 1.2 and 1.4 (95% CI, 1.1-1.3 and 1.2-1.4). Using only the 2003 database, adjusted analysis revealed that patients at highest risk were those in the age range of 15 to 17 years (PR, 2.0; 95% CI, 1.6-2.4) and with the following comorbid conditions: obesity (PR, 2.1; 95% CI, 1.5-2.8), inflammatory bowel disease (PR, 1.8; 95% CI, 1.2-2.7), hematologic malignancy (PR, 2.5; 95% CI, 2.0-3.1), and thoracoabdominal (PR, 1.8; 95% CI, 1.6-2.2) or orthopedic (PR, 2.2; 95% CI, 1.7-2.8) operations. Predictors not associated with DVT included sex and diagnosis of trauma.
Conclusions:
The discharge diagnosis of DVT of the lower extremities has significantly increased since 1997. In addition, teenagers with underlying disorders are at highest risk for DVT.
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