Determination of risk factors for deep venous thrombosis in hospitalized children

Lan T Vu1, Kerilyn K Nobuhara, Hanmin Lee

  • 1Division of Pediatric Surgery, Department of Surgery, University of California, Box 0570, San Francisco, CA 94143-0570, USA.

Insights

Deep venous thrombosis (DVT) in children has increased since 1997. Teenagers with underlying health conditions are most at risk for this condition.

Area of Science:

  • Pediatric Medicine
  • Vascular Health
  • Epidemiology

Background:

  • Deep venous thrombosis (DVT) is a serious condition that can affect children.
  • Understanding trends and risk factors for pediatric DVT is crucial for effective prevention and treatment.

Purpose of the Study:

  • To investigate the time trends in deep venous thrombosis (DVT) prevalence among pediatric inpatients.
  • To identify risk factors associated with DVT in hospitalized children.

Main Methods:

  • Cross-sectional study utilizing the Healthcare Cost and Utilization Project Kids' Inpatient Database (1997, 2000, 2003).
  • Analysis included pediatric inpatients aged 1-17 years hospitalized for at least 4 days.
  • Prevalence and adjusted prevalence ratios were calculated to assess trends and risk factors.

Main Results:

  • The prevalence of DVT in pediatric inpatients was 4.2 per 1000 discharges.
  • DVT prevalence significantly increased in 2000 and 2003 compared to 1997.
  • Highest risk was observed in adolescents (15-17 years) with obesity, inflammatory bowel disease, hematologic malignancy, or specific surgical procedures.

Conclusions:

  • A significant rise in the discharge diagnosis of lower extremity DVT has been observed since 1997.
  • Teenagers with comorbid conditions represent a high-risk group for DVT.
  • Further research into pediatric DVT prevention and management is warranted.
Abstract

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