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Endogenous N-nitrosation and cancer of the biliary tract
C P Caygill1, S A Leach, F Fernandez
1Public Health Laboratory Service, Communicable Disease Surveillance Centre, London, UK.
IARC Scientific Publications
|January 1, 1991
Abstract:
Evidence is presented that N-nitroso compounds occur in bile from patients who have undergone surgery for gallstones or had gastrectomy and from unoperated persons. It is unlikely, therefore, that local formation of nitrosamines can account for the excess risk for gallbladder cancer in the first two groups. Gastric formation remains the likeliest hypothesis.