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Occurrence of and exposure to N-nitroso compounds in tobacco

A R Tricker¹, R Preussmann

¹Institute of Toxicology and Chemotherapy, German Cancer Research Center, Heidelberg.

IARC Scientific Publications

|January 1, 1991

Abstract:

The concentrations of 21 N-nitroso compounds in smokeless tobaccos are presented. Tobacco-specific nitrosamines accounted for 70-90% of the total identified N-nitroso compounds. Daily exposure of smokeless tobacco users to preformed N-nitroso compounds may exceed 200 micrograms/day in certain populations.

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