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ProCOC: the prostate cancer outcomes cohort study.
Martin Umbehr1, Thomas M Kessler, Tullio Sulser
1Horten Centre for patient oriented research and knowledge transfer, University of Zurich, University Hospital of Zurich, Postfach Nord, 8091 Zurich, Switzerland. martin.umbehr@usz.ch
BMC Urology
|June 19, 2008
Summary
This prospective study will investigate localized prostate cancer to improve early diagnosis and treatment choices. It aims to identify prognostic biomarkers and understand treatment impacts on quality of life for better patient outcomes.
Area of Science:
- Oncology
- Urology
- Clinical Research
Background:
- Prostate cancer diagnosis and treatment decisions remain challenging.
- Understanding treatment impact on quality of life is crucial for patient care.
- Prognostic biomarkers are needed for predicting disease course.
Purpose of the Study:
- To address unanswered questions in localized prostate cancer management.
- To evaluate the influence of treatment modalities on quality of life.
- To identify novel prognostic biomarkers for prostate cancer.
Main Methods:
- Prospective, multi-center cohort study in Zurich, Switzerland.
- Inclusion of patients with newly diagnosed localized prostate cancer.
- Collection of clinical data, tissue, blood, and urine samples for bio-banking.
- Minimum ten-year follow-up for morbidity, mortality, and quality of life assessment.
- Biomarker evaluation and bio-bank establishment for future research.
Main Results:
- Data collection ongoing; results to be determined.
- Analysis will focus on treatment effects on patient outcomes and quality of life.
- Biomarker performance for prognosis will be evaluated.
Conclusions:
- The study is expected to yield significant insights into localized prostate cancer prognosis.
- Findings will aid in optimizing treatment strategies and improving patient quality of life.
- Established bio-bank will support future prostate cancer research.
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