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Tracking of blood pressure from childhood to adulthood: a systematic review and meta-regression analysis

Xiaoli Chen1, Youfa Wang

  • 1Center for Human Nutrition, Department of International Health, Bloomberg School of Public Health Johns Hopkins University, 615 N Wolfe St, Baltimore, MD 21205, USA.

Circulation
|June 19, 2008
PubMed

Insights

Blood pressure tracking from childhood into adulthood is robust, with childhood readings predicting adult levels. Early interventions are crucial for managing hypertension risk.

Area of Science:

  • Cardiovascular Health
  • Pediatric Medicine
  • Epidemiology

Background:

  • Numerous studies have investigated blood pressure (BP) tracking from childhood to adulthood.
  • Existing findings are inconsistent, highlighting a need for systematic analysis.

Purpose of the Study:

  • To systematically analyze the evidence for blood pressure tracking from childhood into adulthood.
  • To quantify the strength of BP tracking and identify influencing factors.

Main Methods:

  • A systematic literature search was performed on PubMed for studies published between 1970 and 2006.
  • 50 cohort studies, providing 617 systolic BP and 547 diastolic BP data points, were included in a meta-analysis.
  • Random-effects meta-regression was used to analyze the data.

Main Results:

  • Average blood pressure tracking correlation was 0.38 for systolic BP and 0.28 for diastolic BP.
  • BP tracking strength increased with baseline age and decreased with follow-up duration.
  • Tracking did not significantly vary by race or number of measurements.

Conclusions:

  • Evidence strongly supports blood pressure tracking from childhood into adulthood across diverse populations.
  • Childhood BP is a significant predictor of adult BP, underscoring the importance of early intervention.
Abstract

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