The relationship of coffee consumption with mortality
Esther Lopez-Garcia1, Rob M van Dam, Tricia Y Li
1Harvard School of Public Health, Brigham and Women's Hospital, Boston, Massachussetts, USA. esther.lopez@uam.es
Annals of Internal Medicine
|June 19, 2008
Summary
Regular coffee consumption is not linked to increased mortality. Moderate coffee intake may offer a modest benefit for all-cause and cardiovascular disease mortality, warranting further investigation.
Area of Science:
- Epidemiology
- Nutritional Science
- Public Health
Background:
- Limited data exist on coffee's impact on mortality.
- Coffee consumption is widespread and associated with diverse health effects.
Purpose of the Study:
- To investigate the association between coffee consumption and mortality from cardiovascular disease (CVD), cancer, and all causes.
- To analyze sex-specific mortality risks over extended follow-up periods.
Main Methods:
- Prospective cohort study utilizing Cox proportional hazard models.
- Analysis of data from the Health Professionals Follow-up Study and Nurses' Health Study.
- Assessment of coffee consumption and mortality in over 120,000 men and women.
Main Results:
- Coffee consumption showed an inverse association with all-cause mortality in both men and women, particularly with higher intake levels.
- This association was primarily driven by a reduced risk of cardiovascular disease (CVD) mortality and was independent of caffeine.
- No significant association was found between coffee consumption and cancer mortality.
Conclusions:
- Regular coffee consumption does not increase mortality risk.
- A potential modest benefit of coffee on all-cause and CVD mortality warrants further research.
- Self-reported coffee intake may introduce measurement error.
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