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Related Concept Videos

Interfacial Electrochemical Methods: Overview01:06

Interfacial Electrochemical Methods: Overview

Interfacial electrochemical methods focus on the phenomena occurring at the boundary between an electrode and a solution, as opposed to bulk methods that concentrate on the solution's overall properties. These interfacial methods are classified as either static or dynamic based on the presence of a nonzero current in the electrochemical cell and the consistency of analyte concentrations. Static methods, such as potentiometry, measure the cell's potential without any significant current passing...
Chemistry of the Cell02:58

Chemistry of the Cell

The cell is chemically composed of water, organic molecules and inorganic ions.
Water
The polarity of the water molecule and its resulting hydrogen bonding makes water a unique substance with special properties that are intimately tied to the processes of life. Life originally evolved in an aqueous environment, and most of an organism’s cellular chemistry and metabolism occur inside the aqueous contents of the cell’s cytoplasm. Special properties of water are its high heat capacity and heat of...
Protein-protein Interfaces02:04

Protein-protein Interfaces

Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a polypeptide...
Surface Active Agents01:27

Surface Active Agents

Surfactants, named for their behavior at interfaces, positively adsorb at the interfaces of two phases, reducing interfacial tension. Their versatility as emulsifiers, detergents, and foaming agents stems from this ability. Surfactants, often termed amphiphiles, share the property of amphipathy, with molecules having both hydrophilic and hydrophobic portions. The hydrophilic part is called the head, and the hydrophobic part, including an elongated alkyl substituent, forms the tail.Surfactants...

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Microfluidic Tools for Probing Fungal-Microbial Interactions at the Cellular Level
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Small molecules and chemical tools at the interface.

Robert H Newman1, Jin Zhang

  • 1Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA.

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Chemical biology advances understanding of complex biological processes. Future research will focus on the intersection of chemistry and biology.

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Area of Science:

  • * Chemical biology
  • * Molecular mechanisms
  • * Biological processes

Background:

  • * Growing understanding of molecular mechanisms driving complex biological processes.
  • * The expanding role of chemical biology in scientific discovery.
  • * The 2008 American Society for Biochemistry and Molecular Biology meeting highlighted key advancements.

Framework:

  • * Research at the interface of chemistry and biology.
  • * Exploring molecular mechanisms through chemical tools.
  • * Integrating chemical approaches to study biological systems.

Implementation:

  • * Showcasing recent progress in chemical biology.
  • * Utilizing chemical probes to investigate biological pathways.
  • * Developing novel chemical methodologies for biological research.

Implications:

  • * Expanding the scope of chemical biology research.
  • * Informing future directions in molecular and biological sciences.
  • * Fostering interdisciplinary collaboration between chemistry and biology.