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Updated: Jul 4, 2026

Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
Published on: May 6, 2018
Congenital nephrotic syndrome of the finnish type
Abstract:
SummaryCongenital Nephrotic Syndrome of the Finish type (CNF) is a rare and severe disease. A neonate with CNF is described. The diagnosis carries a dramatically poorer prognosis than nephrotic syndrome diagnosed after one year. The clinical course is one of persistent oedema and recurrent infections leading to death. The gene for the Finish type has been mapped to the long arm of chromosome 19. Case reports show it to be responsive to captopril and indomethacin. It is uniformly resistant to steroids and immunosuppressive drugs.
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