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Antenatal hydronephrosis: infants with minor postnatal dilatation do not need prophylaxis

Karl-Johan Lidefelt1, Maria Herthelius

  • 1Department of Paediatrics, Karolinska University Hospital, Stockholm, Sweden. karl-johan.lidefelt@karolinska.se

Pediatric Nephrology (Berlin, Germany)
|June 19, 2008
PubMed

The aim of this study was to determine the occurrence of urinary tract infection (UTI) in infants with antenatal renal pelvis dilatation (ARPD). Consecutive ultrasound (US) screening of 14,000 pregnant women detected ARPD >or=5 mm in 106 foetuses. After birth, two US examinations were performed: on the fifth to seventh day and during the third week of life. The findings were considered normal when renal pelvis dilatation (RPD) was or=15 mm, vesicoureteric reflux (VUR) grades III-V and suspected obstruction. In 53/103 babies, both US examinations were normal, three had VUR grade I. Two girls had UTI at 18 and 24 months of age, respectively. Among the 50 infants with abnormal initial US, six had VUR, of which four were high grade (IV-V). All four developed UTI. We conclude that UTI is uncommon in infants with two normal postnatal US examinations. Routine use of antibacterial prophylaxis in these infants therefore cannot be recommended.

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