Related Experiment Video
Updated: Aug 8, 2026

Functional Complementation Analysis (FCA): A Laboratory Exercise Designed and Implemented to Supplement the Teaching of Biochemical Pathways
Published on: June 24, 2016
Catabolite modulator factor: a possible mediator of catabolite repression in bacteria
Abstract:
Water soluble extracts of Escherichia coli cells have been found to exert an extremely strong repressive effect upon the expression of catabolite sensitive operons. The compound responsible for this activity has been partially purified and proves to be of low molecular weight and heat stable. The effect of this compound, hereafter designated as catabolite modulator factor, is only partially antagonized by adenosine 3':5'-cyclic monophosphate. The possible role of catabolite modulator factor in the physiological regulation of catabolite repression is discussed.
Related Concept Videos
Prokaryotic Transcriptional Activators and Repressors
Transcription of prokaryotic...
Master Transcription Regulators
Prokaryotic Transcriptional Activators and Repressors
Transcription of prokaryotic...
Amino Acid Catabolism
Inducible Operons: lac Operon
Stringent Response in E. coli

