[Propofol-induced hallucinations and dreams]
Virginie Marchaisseau1, Aurélie Molia, Emmanuelle Herlem
1Centre Régional de Pharmacovigilance, Centre Hospitalier Universitaire, Reims, France.
Abstract:
Through a review of both the cases in the national pharmacovigilance database and the literature, we evaluated the importance of propofol-induced hallucinations and dreams which are not mentioned in the propofol Summaries of Product Characteristics (SPC). Postoperative hallucinations occurring in patients anaesthetized by propofol is not exceptional even with low doses of propofol. Most of the hallucinations are described as pleasant with a frequent "sexual connotation", uninhibited behavior or a verbal expression of patient's intimate thoughts. In the same way, many studies about anaesthetics highlight the supporting role of propofol in the occurrence of pleasant dreams. Finally these effects should be mentioned in the propofol SPC due to the legal implication they might lead to.
Related Concept Videos
Sedatives and Hypnotics Drugs: Miscellaneous Agents
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Parenteral Anesthetics: Overview
Lucid Dreaming
Studies have shown...
Positive Symptoms Schizophrenia: Hallucinations and Delusions
Hallucinations
Hallucinations in...
Hallucinogens and Psychedelics
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains delta-9-tetrahydrocannabinol (THC)...
Sedatives and Hypnotics Drugs: Barbiturates

