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The Brugada type 1 electrocardiographic pattern is common among Filipinos

Giselle Gervacio-Domingo1, Jessore Isidro, Jose Tirona

  • 1University of Phillipines-Phillipines General Hospital, Section of Cardiology, Taft Ave, Manila, 1000 Philippines. gdomingo@zpdee.net

Journal of Clinical Epidemiology
|June 20, 2008
PubMed

Insights

The Brugada type 1 electrocardiographic (ECG) pattern, a marker for sudden death, was found in 0.2% of the Philippine population. This Brugada ECG pattern is common among Filipinos, necessitating further risk assessment.

Area of Science:

  • Cardiology
  • Epidemiology
  • Genetics

Background:

  • Sudden unexplained death syndrome (SUDS) is prevalent in Southeast Asia, often preceded by ventricular fibrillation.
  • The Brugada type 1 electrocardiographic (ECG) pattern, characterized by J point and coved ST elevation in right precordial leads, is a known SUDS marker.
  • The prevalence of the Brugada type 1 ECG pattern in the general population remains unknown.

Purpose of the Study:

  • To determine the prevalence of the Brugada type 1 ECG pattern in the general population of the Philippines.
  • To assess the prevalence of any type of Brugada ECG pattern within the same population.

Main Methods:

  • A cross-sectional nationwide survey was conducted in the Philippines in 2003.
  • A stratified multistage sampling design ensured coverage across all regions and provinces.
  • Electrocardiograms (ECGs) were performed on all surveyed adults to identify Brugada patterns.

Main Results:

  • The Brugada type 1 (coved) ECG pattern was identified in 0.2% of the Philippine population (95% CI 0.03%-0.36%).
  • In males, the prevalence of the Brugada type 1 ECG pattern was 0.3%.
  • The prevalence of any type of Brugada ECG pattern was 2% (95% CI 1.5%-2.6%).

Conclusions:

  • The Brugada ECG pattern is relatively common among Filipinos.
  • Further research is required to ascertain the risk of sudden death in individuals with the Brugada marker in the general population.
Abstract

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