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The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
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Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
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Eikenella corrodens as a causative agent for neonatal conjunctivitis.

Manpreet S Chhabra1, William W Motley, Joel E Mortensen

  • 1Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|June 20, 2008
PubMed
Summary

Ophthalmia neonatorum, a common neonatal eye infection, can stem from various agents. This report details a rare case of neonatal conjunctivitis caused by Eikenella corrodens, a bacterium typically found in the human mouth.

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Area of Science:

  • Ophthalmology
  • Microbiology
  • Neonatology

Background:

  • Ophthalmia neonatorum is a prevalent eye infection in newborns, with bacterial causes being significant.
  • Common bacterial culprits include Neisseria gonorrhoea and Chlamydia trachomatis.
  • Eikenella corrodens is a Gram-negative bacillus, part of normal human flora, increasingly implicated in infections.

Observation:

  • A case of neonatal conjunctivitis was observed.
  • The infection was caused by Eikenella corrodens.
  • This bacterium is typically found in the oral cavity and genitourinary tract.

Findings:

  • Eikenella corrodens was identified as the causative agent of neonatal conjunctivitis in this case.
  • This represents a less common etiology for neonatal bacterial conjunctivitis.
  • The bacterium's slow-growing and fastidious nature can pose diagnostic challenges.

Implications:

  • Highlights the potential for Eikenella corrodens to cause neonatal ophthalmia.
  • Broadens the spectrum of recognized bacterial pathogens responsible for neonatal conjunctivitis.
  • Suggests the need for awareness among clinicians regarding this rare but possible cause.