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Related Experiment Video

Updated: Jul 4, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Risperidone-induced sexual dysfunction in a prepubertal child - a case report.

O Wadoo¹, N Chalhoub

¹Mersey Care NHS Trust, Psychiatry, Southport, Merseyside, UK. owadoo@nhs.net

Journal of Psychopharmacology (Oxford, England)

|June 20, 2008

Summary

A child experienced frequent penile erections while treated with risperidone and atomoxetine for ADHD and motor tics. Symptoms resolved after discontinuing risperidone, highlighting potential side effects of atypical antipsychotics in pediatric psychiatric care.

Related Experiment Videos

Last Updated: Jul 4, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Area of Science:

Child and Adolescent Psychiatry
Pediatric Neurology
Pharmacology

Background:

Attention deficit hyperactivity disorder (ADHD) and motor tics are common pediatric psychiatric conditions.
Risperidone, an atypical antipsychotic, and atomoxetine, a selective norepinephrine reuptake inhibitor, are frequently used in managing these disorders.
Understanding the adverse effect profiles of these medications is crucial for safe and effective treatment.

Observation:

A pediatric patient diagnosed with ADHD and motor tics was treated with a combination of risperidone and atomoxetine.
During the course of this treatment, the child developed frequent, unsolicited penile erections.
These erections ceased upon the discontinuation of risperidone, with no recurrence.

Findings:

The co-administration of risperidone and atomoxetine in a pediatric patient with ADHD and motor tics was associated with the adverse event of frequent penile erections.
The resolution of priapism following the cessation of risperidone suggests a causal link between this atypical antipsychotic and the observed side effect.
Atomoxetine was continued without recurrence of the adverse event.

Implications:

Clinicians prescribing atypical antipsychotics, such as risperidone, for pediatric psychiatric disorders should be vigilant for the potential adverse effect of priapism.
This case underscores the importance of thorough medication review and monitoring for rare but significant side effects in children.
Further investigation into the specific mechanisms by which risperidone may induce priapism in pediatric populations is warranted.