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Updated: Jul 4, 2026

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
Juxtapapillary cytomegalovirus retinitis with optic neuritis
Alexander S Ioannidis1, James Bacon, Peggy Frith
1Department of Ophthalmology, University College London Hospitals NHS Trust, London, United Kingdom. alexioannidis@hotmail.com
Abstract:
A 49-year-old man with AIDS developed acute monocular visual loss and an ipsilateral swollen optic disc with a large right relative afferent pupillary defect, a nerve fiber bundle visual field defect, and a peripapillary retinal infiltrate. Lumbar puncture disclosed cytomegalovirus (CMV) DNA on polymerase chain reaction (PCR). Treatment with oral valganciclovir produced complete resolution of the visual deficits and the fundus abnormality. This case differs from previously reported cases of CMV optic neuritis in which visual function has been irreversibly lost.
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