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Updated: Jul 4, 2026

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
The safety of the electroconvulsive therapy-aripiprazole combination: four case reports
Vasilios G Masdrakis1, Panagiotis Oulis, Iannis M Zervas
1Department of Psychiatry, Athens University Medical School, Eginition Hospital, Athens, Greece. vmasdrakis@med.uoa.gr
Abstract:
In clinical practice, a proportion of patients with psychotic or mood disorders are treated with electroconvulsive therapy (ECT) while receiving concomitantly antipsychotic and/or other psychotropic agents. Aripiprazole is a second-generation antipsychotic that seems to have a favorable side-effect profile. However, to the best of our knowledge, there are, as yet, no available reports on the safety of ECT-aripiprazole combination. We report the cases of 4 female inpatients--3 suffering from major depression and 1 from schizophrenia--who underwent ECT--1 of them twice--while receiving aripiprazole (10-15 mg/d), as part of their regimen. In all cases, the combination was well tolerated and only minimal side effects were reported.
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