Related Experiment Video
Updated: Jul 4, 2026
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
[OCT-3 documentation of spontaneous resolution of blunt macular hole injury: a case study]
G Souteyrand1, I Sillaire, V Thomas
1Service d'Ophtalmologie, CHU Clermont-Ferrand, Hôpital Gabriel Montpied, Clermont-Ferrand. georgessouteyrand@yahoo.fr
Objective:
To report a case of a spontaneous resolution of a macular hole resulting from injury.
Observation:
A 17-year-old man experienced a blunt injury: fundus examination found a full-thickness macular hole. It was studied with a clinical exam and optical coherence tomography images. After two weeks, the macular hole spontaneously disappeared.
Discussion:
Blunt injury is the most frequent ocular injury. The consequences can be very serious because of possible lesions in the macular area: the visual function prognosis can therefore be disastrous. Macular holes can have a good prognosis, and spontaneous closure is sometimes observed. This report attempts to explain the mechanisms.
Conclusion:
Disappearance of a macular hole resulting from injury can occur spontaneously, especially in young patients. OCT is today indispensable, making it possible to follow up the injury and its consequences objectively, reliably and with very good reproducibility.
