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Signal amplification by conjugate addition for differential sensing with synthetic pores

Shinya Hagihara1, Hiroyuki Tanaka, Stefan Matile

  • 1Department of Organic Chemistry, University of Geneva, Geneva, Switzerland.

Organic & Biomolecular Chemistry
|June 20, 2008
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Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
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