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Updated: Jul 4, 2026
05:30
Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
Published on: October 31, 2025
The esophageal remnant after gastric interposition
X B D'Journo1, J Martin, P Ferraro
1Department of Surgery, Université de Montréal, Thoracic Surgery Division, Quebec, Canada.
Summary
Gastric interposition after esophagectomy can cause significant reflux esophagitis in the remaining esophagus. Factors like gastric function and surgical technique influence mucosal damage, impacting patient quality of life.
Area of Science:
- Gastroenterology
- Surgical Reconstruction
- Esophageal Diseases
Background:
- Gastric interposition is a common reconstruction method after esophagectomy.
- However, it is linked to reduced quality of life and significant reflux esophagitis in the esophageal remnant.
Purpose of the Study:
- To review factors influencing the esophageal remnant mucosa after gastric interposition.
- To discuss prevention and treatment strategies for esophagitis in this context.
Main Methods:
- A Medline search was conducted.
- References from reviewed articles were used to identify additional relevant studies.
Main Results:
- Reflux disease is a frequent consequence of gastric interposition, affecting approximately 50% of patients.
- Mucosal damage (esophagitis) can progress from inflammation to metaplasia.
- No clear correlation exists between symptoms and mucosal damage, necessitating endoscopic evaluation.
Conclusions:
- Surgical factors (anastomosis level, reconstruction route, patient positioning) and patient-specific factors (esophageal/gastric function) impact remnant esophageal mucosa.
- Further research into in vivo models may elucidate mechanisms of mucosal damage.
- Improvements in gastric transplant reconstruction are needed for better outcomes.
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