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Ciguatera fish poisoning with elevated muscle enzymes and abnormal spinal MRI

Mohammad Wasay1, Amanullah Sarangzai, Ather Siddiqi

  • 1Department of Neurology, The Aga Khan University, Karachi, Pakistan. mohammad.wasay@aku.edu

The Southeast Asian Journal of Tropical Medicine and Public Health
|June 21, 2008
PubMed

Insights

Ciguatera fish poisoning can cause respiratory failure and abnormal cervical spinal MRIs, previously undescribed findings. These insights may explain L'hermitte phenomenon and suggest respiratory muscle involvement in severe cases.

Area of Science:

  • Neurology
  • Toxicology
  • Medical Imaging

Background:

  • Ciguatera fish poisoning is a significant public health concern.
  • Neurological manifestations are common, but severe complications are rare.

Observation:

  • Three cases of ciguatera fish poisoning were analyzed.
  • One patient experienced fatal respiratory failure.
  • Abnormal cervical spinal MRI findings were observed in one patient.

Findings:

  • Novel cervical spinal MRI findings in ciguatera fish poisoning are reported.
  • These MRI findings elucidate the mechanism of L'hermitte phenomenon.
  • Elevated muscle enzymes were noted in two patients.

Implications:

  • Respiratory failure, though rare, may involve respiratory muscle dysfunction.
  • This study highlights the potential for severe neurological and respiratory complications.
  • Advanced imaging like MRI can reveal underlying mechanisms of poisoning symptoms.

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