Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 4, 2026

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research
05:16

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Published on: October 27, 2023

Indirect pulp therapy and stepwise excavation.

Lars Bjørndal1

  • 1Department of Cariology and Endodontics, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. lb@odont.ku.dk

Journal of Endodontics
|July 2, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Understanding the Content and Purpose of S3 Clinical Practice Guidelines in Dentistry.

International endodontic journal·2026
Same author

Targeting Dental Pulp Stem Cell Senescence: A Potential Strategy for Improving Regenerative Endodontic Procedures.

Bioengineering (Basel, Switzerland)·2026
Same author

Deep Caries Management: EFCD-ESE-ORCA S3-Level Clinical Practice Guideline.

International endodontic journal·2026
Same author

Deep Caries Management: EFCD-ESE-ORCA S3-Level Clinical Practice Guideline.

Caries research·2026
Same author

Deep caries management: EFCD-ESE-ORCA S3-level clinical practice guideline.

Clinical oral investigations·2026
Same author

Consensus-Based Recommendations on Pulp Therapies in Primary and Permanent Teeth: IAPD Porto Forum.

International journal of paediatric dentistry·2026
Same journal

CLINICAL PARAMETER-BASED EVALUATION OF RESTORATIVE TREATMENT DIFFICULTY IN ENDODONTICALLY TREATED TEETH.

Journal of endodontics·2026
Same journal

Clinical Outcome of Replanted Avulsed Anterior Teeth: A Retrospective Cohort Study.

Journal of endodontics·2026
Same journal

Mahidol study 3: Post-operative Effect and Adverse Events of Regenerative Endodontic Procedures in Immature Permanent Teeth.

Journal of endodontics·2026
Same journal

Non-Surgical Management of Horizontal Root Fracture with Necrotic Apical Segment and Coronal Cervical Abfraction Using Mineral Trioxide Aggregate: Case Report.

Journal of endodontics·2026
Same journal

Identification of pain-related biomarkers and the associated potential molecular regulation mechanism in pulpitis by bioinformatics method.

Journal of endodontics·2026
Same journal

AI Prognostic Models in Endodontics: Scoping Review and Clinical Gap Analysis for Retreatment vs Microsurgery Decision Support.

Journal of endodontics·2026
See all related articles

Optimal randomized clinical studies are lacking for deep carious lesions. Current observational studies show stepwise excavation and indirect pulp treatment avoid pulp exposure, but the best approach remains unclear.

Area of Science:

  • Dentistry
  • Cariology
  • Endodontics

Background:

  • Deep carious lesions present a treatment dilemma with a lack of high-quality evidence.
  • Existing systematic reviews are based on limited studies, highlighting the need for robust clinical trials.

Purpose of the Study:

  • To review current treatment concepts for deep carious lesions.
  • To discuss findings from observational studies and ongoing clinical trials.
  • To present treatment guidelines for managing deep caries.

Main Methods:

  • Review of recent systematic reviews on deep carious lesion management.
  • Analysis of observational studies on indirect pulp treatment and stepwise excavation.
  • Description of a modified stepwise excavation technique.

Related Experiment Videos

Last Updated: Jul 4, 2026

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research
05:16

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Published on: October 27, 2023

  • Information on the ongoing Caries and Pulp (CAP) trial.

    • Main Results:

    • Observational studies indicate indirect pulp treatment and stepwise excavation can prevent pulp exposure.
    • Evidence is insufficient to determine the optimal treatment between these approaches.
    • A modified stepwise excavation aims to arrest lesions non-invasively.

    Conclusions:

    • High-quality randomized clinical trials are crucial for definitive treatment recommendations.
    • Stepwise excavation is being investigated in a multi-center trial comparing 1-visit vs. 2-visit approaches.
    • Guidelines for managing deep caries are presented based on current evidence and ongoing research.