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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Updated: Jul 4, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

MRI in multiple sclerosis: current status and future prospects.

Rohit Bakshi1, Alan J Thompson, Maria A Rocca

  • 1Center for Neurological Imaging, Partners Multiple Sclerosis Center, Departments of Neurology and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

The Lancet. Neurology
|June 21, 2008
PubMed
Summary
This summary is machine-generated.

Advanced magnetic resonance imaging (MRI) techniques offer new hope for diagnosing and managing multiple sclerosis (MS). These methods aim for earlier detection, better phenotype identification, and deeper understanding of MS pathophysiology.

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Last Updated: Jul 4, 2026

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Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis
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Area of Science:

  • Neuroimaging
  • Radiology
  • Neurology

Background:

  • Multiple sclerosis (MS) management relies on accurate diagnosis and monitoring.
  • Emerging and refined magnetic resonance imaging (MRI) techniques show promise for MS research and clinical application.

Purpose of the Study:

  • To review recent advancements in MRI for multiple sclerosis.
  • To discuss the potential of these advanced techniques for diagnosis, phenotype identification, and understanding MS pathophysiology.

Main Methods:

  • Review of recent developments in advanced MRI techniques.
  • Discussion of magnetic resonance spectroscopy, diffusion imaging, cell-specific imaging, myelin water fraction imaging, and ultra-high-field MRI.
  • Forward look at refinements in spinal-cord, optic-nerve, perfusion, and functional MRI.

Main Results:

  • Advanced MRI methods require assessment for earlier diagnosis and phenotype identification.
  • Improved post-processing enhances information extraction from MRI images.
  • New techniques like magnetic resonance spectroscopy and diffusion imaging offer greater sensitivity, specificity, and insights into connectivity and myelin content.

Conclusions:

  • Recent MRI developments hold significant potential for improving the diagnosis and monitoring of MS.
  • Further refinements in various MRI modalities are expected to enhance our understanding of MS pathophysiology.
  • Advanced MRI is poised to significantly improve clinical management and research in multiple sclerosis.