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Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

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Related Experiment Video

Updated: Jul 4, 2026

A Modified Surgical Technique for Kidney Transplantation in Mice
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A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

Long-term renal outcomes after delayed graft function.

Sri G Yarlagadda1, Christina L Klein, Alkesh Jani

  • 1Department of Medicine, Section of Nephrology, Yale School of Medicine, New Haven, CT, USA.

Advances in Chronic Kidney Disease
|June 21, 2008
PubMed
Summary
This summary is machine-generated.

Delayed graft function (DGF) is common after kidney transplants, often requiring dialysis post-surgery. This complication impacts patient recovery, increases costs, and leads to poorer long-term kidney graft survival.

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Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET
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Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET
17:13

Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET

Published on: April 28, 2013

Area of Science:

  • Nephrology
  • Transplantation Immunology
  • Surgical Complications

Background:

  • Delayed graft function (DGF) is the most frequent complication following kidney transplantation.
  • It is characterized by kidney allograft dysfunction in the immediate post-transplant period.
  • While a standardized definition is absent, DGF is typically defined by the need for dialysis within the first week post-transplant.

Purpose of the Study:

  • To review identified risk factors contributing to DGF.
  • To examine the impact of DGF on both allograft and patient outcomes.
  • To discuss the immunologic and nonimmunologic mechanisms underlying DGF.

Main Methods:

  • Literature review of identified DGF risk factors.
  • Analysis of studies reporting on DGF incidence and outcomes.
  • Synthesis of information on immunologic and non-immunologic mechanisms.

Main Results:

  • DGF is associated with prolonged hospital stays and increased transplantation costs.
  • Occurrence of DGF correlates with a higher incidence of acute rejection.
  • DGF negatively impacts long-term kidney allograft survival and function.

Conclusions:

  • DGF presents significant challenges in kidney transplantation.
  • Understanding risk factors and mechanisms is crucial for improving patient and graft outcomes.
  • Mitigating DGF is essential for enhancing the success of kidney allografts.