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Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
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Steroid receptor coactivator-1 from brain physically interacts differentially with steroid receptor subtypes

Heather A Molenda-Figueira1, Suzanne D Murphy, Katherine L Shea

  • 1Center for Neuroendocrine Studies, Neuroscience, and Behavior Program, University of Massachusetts, Amherst, MA 01003, USA.

Endocrinology
|June 21, 2008
PubMed
Summary

Steroid receptor coactivator-1 (SRC-1) interacts with estrogen (ER) and progestin receptors (PR) in the brain. These interactions are ligand-dependent and vary by receptor subtype and brain region, impacting steroid-regulated behaviors.

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