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Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

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Published on: March 29, 2022

Ciliary body thickness and refractive error in children.

Melissa D Bailey1, Loraine T Sinnott, Donald O Mutti

  • 1Ohio State University College of Optometry, Columbus, Ohio, USA. mbailey@optometry.osu.edu

Investigative Ophthalmology & Visual Science
|June 21, 2008
PubMed
Summary

Thicker ciliary body measurements in children are linked to myopia and longer axial length. This finding suggests a potential relationship between ciliary body structure and refractive error development.

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Area of Science:

  • Ophthalmology
  • Pediatric Optometry
  • Biomedical Optics

Background:

  • Refractive error, particularly myopia, is a growing concern in school-aged children.
  • Understanding the anatomical factors contributing to refractive error is crucial for early detection and intervention.

Purpose of the Study:

  • To investigate the association between ciliary body thickness (CBT) and refractive error in school-aged children.
  • To determine if CBT correlates with axial length, a key determinant of refractive error.

Main Methods:

  • Anterior segment OCT was used to measure CBT at multiple points posterior to the scleral spur in 53 children (ages 8-15).
  • Cycloplegic refractive error and axial length were measured using an autorefractor and optical biometer, respectively.
  • Multilevel regression models analyzed the relationship between CBT, refractive error, and axial length.

Main Results:

  • Thicker ciliary body measurements at 2 and 3 mm posterior to the scleral spur were significantly associated with increased myopia.
  • Increased CBT measurements also correlated with longer axial lengths.
  • The study demonstrated good between-visit repeatability for ciliary body measurements.

Conclusions:

  • Ciliary body thickness is associated with myopia and longer axial length in children.
  • Further research is warranted to explore this relationship in animal models and to establish the temporal sequence between ciliary muscle thickening and myopia onset.