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Related Experiment Video

Updated: Jul 4, 2026

Cell-Lineage Guided Mass Spectrometry Proteomics in the Developing (Frog) Embryo
09:18

Cell-Lineage Guided Mass Spectrometry Proteomics in the Developing (Frog) Embryo

Published on: April 21, 2022

Chemical technologies for probing embryonic development.

Ilya A Shestopalov1, James K Chen

  • 1Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Chemical Society Reviews
|June 24, 2008
PubMed
Summary
This summary is machine-generated.

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Chemical biology tools offer precise control over gene function during embryogenesis. This review explores chemical methods for visualizing embryonic development and controlling gene activity, highlighting future research directions.

Area of Science:

  • Developmental Biology
  • Chemical Biology
  • Molecular Biology

Background:

  • Embryogenesis involves complex cell proliferation, migration, and differentiation.
  • Understanding embryogenesis requires interdisciplinary approaches, integrating chemical biology.
  • Molecular and systems-level insights are crucial for developmental biology.

Purpose of the Study:

  • To provide an overview of chemical tools used in developmental biology research.
  • To focus on methods enabling spatiotemporal control of gene function.
  • To highlight techniques for visualizing embryonic patterning.

Main Methods:

  • Review of chemical tools and methodologies.
  • Focus on chemical genetics and chemical probes.
  • Discussion of imaging techniques in developmental biology.

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A Semi-high-throughput Imaging Method and Data Visualization Toolkit to Analyze C. elegans Embryonic Development
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A Semi-high-throughput Imaging Method and Data Visualization Toolkit to Analyze C. elegans Embryonic Development

Published on: October 29, 2019

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Last Updated: Jul 4, 2026

Cell-Lineage Guided Mass Spectrometry Proteomics in the Developing (Frog) Embryo
09:18

Cell-Lineage Guided Mass Spectrometry Proteomics in the Developing (Frog) Embryo

Published on: April 21, 2022

A Semi-high-throughput Imaging Method and Data Visualization Toolkit to Analyze C. elegans Embryonic Development
06:49

A Semi-high-throughput Imaging Method and Data Visualization Toolkit to Analyze C. elegans Embryonic Development

Published on: October 29, 2019

Main Results:

  • Chemical biology tools offer precise spatiotemporal control over gene function.
  • Various chemical methods facilitate the visualization of embryonic patterning.
  • Current approaches have limitations that need addressing.

Conclusions:

  • Chemical biology is essential for advancing developmental biology research.
  • Further development of chemical tools is needed for deeper insights into embryogenesis.
  • Interdisciplinary collaboration is key to overcoming future challenges in understanding embryonic development.