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Prevalence of left ventricular hypertrophy detected by Cornell voltage-duration product in a hypertensive population
Vivencio Barrios1, Carlos Escobar, Alberto Calderon
1Department of Cardiology, Hospital Ramón y Cajal, Madrid, Spain. vbarriosa@meditex.es
Insights
Left ventricular hypertrophy (LVH) affects nearly a quarter of hypertension patients in Spanish clinics. The Cornell voltage-duration product (CorP) is a valuable tool for detecting LVH in general practice settings.
Area of Science:
- Cardiology
- Hypertension Research
- Diagnostic Markers
Background:
- Left ventricular hypertrophy (LVH) is a significant cardiovascular risk factor in hypertensive patients.
- Early detection and management of LVH are crucial for reducing overall cardiovascular risk.
- The Cornell voltage-duration product (CorP) is recognized as a reliable electrocardiogram (ECG) marker for LVH.
Purpose of the Study:
- To determine the prevalence of LVH in patients with essential hypertension.
- To assess the utility of the CorP method for LVH detection in a general practice setting.
Main Methods:
- A multicenter, cross-sectional survey was conducted among outpatient hypertensive patients in Spain.
- Left ventricular hypertrophy (LVH) was identified using the Cornell voltage-duration product (CorP) criterion (>2.440 mm.ms) on ECG.
- ECG recordings were independently assessed to detect LVH.
Main Results:
- The study evaluated 782 hypertensive patients with a mean age of 66.1 years; 50.6% were male.
- Blood pressure control was inadequate in 86.8% of the study population.
- Left ventricular hypertrophy (LVH) was detected in 23.4% of patients via the CorP method. Predictors included prior LVH, retinopathy, age, grade II hypertension, and male gender.
Conclusions:
- Approximately one-quarter of hypertensive patients in Spanish outpatient clinics exhibit LVH, as identified by the CorP criterion.
- The CorP method demonstrates utility for detecting LVH within general practice settings.
- These findings underscore the importance of screening for LVH in hypertensive populations.
Introduction:
Detection and treatment of left ventricular hypertrophy (LVH) in hypertension is important in order to reduce cardiovascular risk. The product of QRS voltage and duration (e.g. Cornell voltage-duration product; CorP), is a good marker of LVH and the current study was designed to determine the prevalence of LVH in patients with essential hypertension treated in general practice.
Methods:
This study was a multicenter, cross-sectional survey in outpatient hypertensive patients attending clinics across Spain. The primary endpoint for detection of LVH was a CorP >2.440 mm.ms on ECG recordings, which were independently assessed.
Results:
Seven hundred and eighty-two patients were evaluated (66.1+/-10.4 years; 50.6% males; body mass index 28.2+/-6.1 kg/m2) with a mean baseline blood pressure (BP) of 155.7+/-17.7/90.8+/-10.6 mmHg. Only 13.2% of the study population had BP that was adequately controlled. LVH was detected in 23.4% of patients using the CorP method. Predictors of LVH were prior history of LVH, hypertensive retinopathy, age, grade II hypertension and male gender.
Conclusions:
Almost one-quarter of hypertensive patients who attended outpatient clinics in Spain had LVH detected by CorP. The CorP criterion appears to be a useful method for detecting LVH in general practice.
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