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Updated: Jul 4, 2026

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Refractory access disorders and the organization of concrete and abstract semantics: do they differ?
A Cris Hamilton1, H Branch Coslett
1Department of Neurology, University of Pennsylvania, 3 West Gates, 3400 Spruce St, Philadelphia, PA 19103, USA.
Abstract:
Patients with 'refractory semantic access deficits' demonstrate several unique features that make them important sources of insight into the organization of semantic representations. Here we attempt to replicate several novel findings from single-case studies reported in the literature. Patient UM-103 displays the cardinal features of a 'refractory semantic access deficit' and showed many of the same effects of semantic relatedness reported in the literature. However, when probing concrete and abstract words, this patient revealed very different patterns of performance compared to two previously reported patients. We discuss the implications of our data for models of semantic organization of abstract and concrete words.
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