Related Experiment Video
Updated: Jul 4, 2026

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma
Published on: January 12, 2024
Intravascular lymphoma masquerading as Vogt-Koyanagi-Harada syndrome
Patricia J Pahk1, Derrick J Todd, Gregory R Blaha
1Department of Ophthalmology, Lahey Clinic, Burlington, Massachusetts 01805, USA.
Purpose:
To describe the clinical course of a case of intravascular lymphoma.
Design:
Case report.
Methods:
Retrospective chart review.
Results:
A 56-year-old man presented with blurry vision associated with fever and decreased hearing. Ocular exam including fluorescein angiography and OCT was consistent with Vogt-Koyanagi-Harada syndrome and the patient initially improved with corticosteroids. Clinical deterioration led to further systemic workup and revealed intravascular lymphoma. The patient was started on chemotherapy with resolution of visual complaints.
Conclusions:
Intravascular lymphoma can present as a masquerade of VKH syndrome. Diagnosis can be aided with measurement of LDH and skin biopsy.
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