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Relationship between subtypes of irritable bowel syndrome and severity of symptoms associated with panic disorder
Nagisa Sugaya1, Hisanobu Kaiya, Hiroaki Kumano
1Graduate School of Human Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, JP-359-1192 Saitama, Japan. nagisa@suou.waseda.jp
Objective:
To investigate the relationship between subtypes of irritable bowel syndrome (IBS) and severity of symptoms associated with panic disorder (PD).
Material And Methods:
The study comprised 178 consecutive new PD outpatients. Sixty-four patients met the Rome-II criteria for IBS (IBS[+]; 29 diarrhea-predominant IBS (IBSD), 14 constipation-predominant IBS (IBSC), 21 other types of IBS).
Results:
IBSD patients with agoraphobia avoided a greater number of scenes owing to fear of panic attack than did PD patients without IBS (IBS[-]) and with agoraphobia. IBS[+] patients with avoidant behavior due to fear of IBS symptoms had significantly higher Beck Depression Inventory (BDI) scores and avoided a larger number of scenes owing to fear of panic attack than IBS[+] patients with agoraphobia and without avoidant behavior due to fear of IBS symptoms or IBS[-] patients with agoraphobia.
Conclusions:
The results suggest that the presence of IBSD or avoidant behavior because of fear of IBS symptoms may be associated with a more severe form of agoraphobia, and the latter may also be associated with depression.
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