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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Jul 4, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Software-assisted optic nerve assessment for glaucoma tele-screening.

Albert S Khouri1, Bernard C Szirth, Khadija S Shahid

  • 1Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07103, USA. albertkhouri@hotmail.com

Telemedicine Journal and E-Health : the Official Journal of the American Telemedicine Association
|June 24, 2008
PubMed
Summary
This summary is machine-generated.

New software effectively calculates optic nerve head (ONH) cup-to-disc ratio (CDR) from digital images. This tool aids in glaucoma screening, allowing individuals with varying ophthalmic training to assess CDR accurately.

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Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition
06:09

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition

Published on: August 18, 2023

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Glaucoma Diagnostics

Background:

  • Elevated optic nerve head (ONH) cup-to-disc ratio (CDR) is a potential indicator of glaucoma.
  • Accurate CDR assessment traditionally requires a trained ophthalmologist.
  • Digital imaging offers potential for remote or automated analysis.

Purpose of the Study:

  • To evaluate the efficacy of EyeScape software in calculating CDR from digital ONH images.
  • To assess the reproducibility and accuracy of CDR measurements performed by individuals with different levels of ophthalmic training using the software.

Main Methods:

  • Digital stereoscopic ONH images from 28 subjects (normal and glaucoma groups) were analyzed.
  • Three raters with varying expertise (glaucoma specialist, optometrist, trainees) used EyeScape software for CDR calculation.
  • Image analysis was performed on high-resolution monitors, with raters masked to each other's assessments.

Main Results:

  • Reproducibility of CDR measurements was similar across all operator levels.
  • Trainees showed a statistically significant, though small, increase in CDR values for both normal and glaucoma groups.
  • EyeScape software provided CDR calculations (0.00-1.00) after manual contour line placement.

Conclusions:

  • EyeScape software enables CDR evaluation of ONH images by personnel with diverse ophthalmic training backgrounds.
  • Accurate CDR determination is crucial for tele-screening of vision-threatening diseases.
  • The software can assist in identifying individuals with suspicious ONH requiring further specialist examination.