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Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
HIV/AIDS: epidemic update, new treatment strategies and impact on autoimmunity
1Department of Clinical Sciences L. Sacco, University of Milan, Milan, Italy.
Abstract:
Human Immunodeficiency Virus (HIV) infection represents one of the most serious challenges to global public health, since more than 30 million people are living with HIV/AIDS worldwide. Highly active antiretroviral treatment (HAART) introduction has dramatically changed the mortality and morbidity of HIV-affected subjects in industrialized countries but has implied an evolution of many HIV-related aspects, both in the utilisation of new antiretroviral drugs options and in the newly-observed spectrum of HIV-associated diseases, including the rheumatic pathology. Current epidemiological, therapeutic, autoimmune and rheumatic aspects of HIV-1 infection are here discussed.
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