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Updated: Jul 4, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
Published on: September 20, 2016
The molecular genetics of laryngeal cancer
1Department of Otolaryngology, Head and Neck Surgery, Johns Hopkins University School of Medicine, 601 North Caroline Street, Baltimore, MD 21287, USA.
Abstract:
The authors present the clinical relevance of molecular genetics to laryngeal cancer in terms of helping to develop novel diagnostic, prognostic, and therapeutic strategies. They discuss how molecular diagnostics can detect abnormalities in lesions not yet appreciated histologically, and thus detect early recurrences. Patient management with novel targeted therapies for head and neck squamous cell carcinoma in the clinical arena is presented, with treatment options tailored to the individual patient and his or her cancer among them, with the goal of improving clinical outcomes.
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