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Related Experiment Videos

Practice randomization and clinical research. The Indiana experience.

W M Tierney1, M E Miller, S L Hui

  • 1Department of Medicine, Indiana University School of Medicine, Indianapolis.

Medical Care
|July 1, 1991
PubMed
Summary

A well-prepared clinical research laboratory supports scientific investigation. Indiana University

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Area of Science:

  • General Internal Medicine
  • Outpatient Clinical Investigation
  • Health Services Research

Background:

  • Sustained outpatient clinical investigation requires a dedicated research laboratory.
  • The Division of General Internal Medicine at Indiana University has operated such a facility for over 15 years.

Purpose of the Study:

  • To describe the structure and function of a clinical investigation laboratory within an academic general internal medicine practice.
  • To highlight the integration of information systems and randomized patient allocation in facilitating clinical research.

Main Methods:

  • Description of the General Medicine Practice at Regenstrief Health Center.
  • Details on random allocation of subjects for studies.
  • Explanation of data management and patient clinical service utilization tracking systems.

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Main Results:

  • The established infrastructure supports ongoing outpatient clinical investigation.
  • Integration of information systems with a randomized primary care setting has proven effective.
  • Facilitation of successful clinical investigation ventures.

Conclusions:

  • A dedicated and well-structured clinical research laboratory is crucial for sustained scientific investigation.
  • The Indiana University model demonstrates successful integration of clinical practice, information systems, and research.
  • Randomized primary care systems combined with robust data management foster clinical research advancements.