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Related Experiment Videos

Multiple recurrent dermatofibrosarcoma protuberans of the hand.

Efterpi C Demiri1, Dimitrios D Dionyssiou, John M Kirkos

  • 1Department of Plastic Surgery, Aristotle University of Thessaloniki, Greece.

Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS
|June 24, 2008
PubMed
Summary

This case study highlights successful treatment of a recurrent dermatofibrosarcoma protuberans on the hand using radical surgery and a skin flap. The patient achieved a functional outcome with no signs of recurrence after 40 months.

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Area of Science:

  • Dermatologic Surgery
  • Surgical Oncology
  • Hand Surgery

Background:

  • Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive skin cancer.
  • Recurrent DFSP on the hand presents significant surgical challenges.
  • Optimal treatment for DFSP typically involves wide surgical excision.

Observation:

  • A 51-year-old woman with a history of four DFSP recurrences on her hand dorsum.
  • The patient underwent radical surgical excision and reconstruction with a distal ulnar artery skin island flap.
  • Adjuvant radiation therapy was administered post-operatively.

Findings:

  • The patient achieved a functional hand with no evidence of disease recurrence at 40 months post-surgery.
  • Radical excision with wide margins is considered optimal for DFSP.

Related Experiment Videos

  • Less extensive surgery combined with radiotherapy may be a viable alternative for complex cases, preventing mutilation.

    • Implications:

    • This case demonstrates the efficacy of combining radical surgery with flap reconstruction and adjuvant radiotherapy for challenging DFSP.
    • Such combined approaches can preserve hand function while managing aggressive tumors.
    • This strategy may reduce recurrence rates and the risk of metastasis in difficult-to-treat DFSP cases.