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Bath-induced paroxysmal disorders in infancy
Alla Nechay1, John B P Stephenson
1Neurology Department, Paediatric Hospital, Kiev, Ukraine. allanechay@ukr.net
Insights
Infant bathing can trigger paroxysmal disorders like bathing epilepsy. These conditions, including alternating hemiplegia of childhood, hyperekplexia, and pain disorder, involve autonomic symptoms and may be linked to channelopathies.
Area of Science:
- Neurology
- Pediatrics
- Genetics
Background:
- Infant bathing, particularly in normal temperature water, can precipitate paroxysmal disorders.
- Four main diagnostic categories have been identified where bathing acts as a trigger.
Purpose of the Study:
- To review paroxysmal disorders in infants and newborns triggered by bathing.
- To differentiate bathing-induced epilepsy from hot water epilepsy.
Main Methods:
- Literature review focusing on infant bathing in water (36-38°C).
- Analysis of diagnostic categories associated with bathing triggers.
Main Results:
- Identified four categories: bathing epilepsy, alternating hemiplegia of childhood, hyperekplexia, and paroxysmal extreme pain disorder.
- Bathing epilepsy is distinct from hot water epilepsy; some cases may have a genetic basis.
- No convincing evidence for bath-induced infantile syncope was found.
Conclusions:
- Bathing can trigger various paroxysmal disorders in infants.
- These disorders share autonomic manifestations, suggesting potential channelopathy links.
- Further research is needed to understand the underlying mechanisms.
Abstract:
We reviewed those paroxysmal disorders of infancy and of the newborn in which the normal process of bathing may be an important trigger. We focused on infant bathing in normal temperature water (37 degrees C, range 36-38 degrees C) rather than in hot water that is above body temperature. Four principal diagnostic categories emerged: bathing epilepsy, alternating hemiplegia of childhood, hyperekplexia and paroxysmal extreme pain disorder. Bathing or water immersion epilepsy was the best studied and is arguably distinct from hot water epilepsy. The paroxysmal episodes previously attributed to aquagenic urticaria may have been examples of bathing epilepsy with a genetic component. Despite suggestions in the literature to the contrary, no convincing reports of bath-induced infantile syncope have been found. The underlying mechanisms of bath-induced paroxysmal disorders in infancy remain poorly understood, but all have autonomic manifestations and some if not all may be channelopathies.
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