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Targeting the Corticospinal Tract in Neonatal Rats with a Double-Viral Vector using Combined Brain and Spine Surgery
Published on: June 30, 2021
Treatment for neonatal neuralgic amyotrophy
J J van Eijk1, I Cuppen, N van Alfen
1Department of Neurology, Radboud University Nijmegen Medical Centre, The Netherlands. j.vaneijk@neuro.umcn.nl
Summary
A neonate experienced brachial plexus neuropathy and humerus osteomyelitis. Prompt treatment with antibiotics and dexamethasone led to rapid improvement, highlighting effective therapeutic strategies for this rare condition.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
- Orthopedic Surgery
Background:
- Brachial plexus neuropathy, including neuralgic amyotrophy, can affect neonates.
- Osteomyelitis is a serious bone infection requiring prompt diagnosis and treatment.
Observation:
- A 15-day-old neonate presented with symptoms suggestive of brachial plexus neuropathy.
- Imaging and clinical evaluation confirmed concomitant osteomyelitis of the ipsilateral humerus.
Findings:
- The neonate was diagnosed with neuralgic amyotrophy alongside humerus osteomyelitis.
- Treatment involved intravenous antibiotics and oral dexamethasone.
Implications:
- This case underscores the importance of considering concurrent infections in neonatal neurological conditions.
- The rapid clinical improvement suggests a favorable prognosis with timely, multimodal treatment.
- This presentation highlights a rare but treatable cause of neonatal brachial plexus neuropathy.

