Related Experiment Video

Updated: Jul 4, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

Left ventricular longitudinal and radial synchrony and their determinants in healthy subjects

Arnold C Ng1, Da T Tran, Mark Newman

  • 1Department of Cardiology, Liverpool Hospital, University of New South Wales, Sydney, Australia.

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
|June 24, 2008
PubMed

Insights

This study establishes normal reference ranges for left ventricular (LV) synchrony in healthy adults. LV systolic and diastolic synchrony show gender specificity and depend on LV function, unlike radial synchrony.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Mechanics

Background:

  • Left ventricular (LV) synchrony is crucial for cardiac function.
  • Reference values and determinants of LV synchrony in healthy individuals are not well-established.
  • Understanding these factors is essential for accurate echocardiographic assessment.

Purpose of the Study:

  • To determine reference values for LV longitudinal and radial synchrony in healthy adults.
  • To investigate the impact of physiologic variables (age, gender) on LV synchrony.
  • To compare different echocardiographic methods for assessing LV synchrony.

Main Methods:

  • Prospective study of 122 healthy volunteers (age 19-68).
  • Tissue Doppler imaging used for longitudinal systolic (SDTs) and diastolic (SDTe) synchrony.
  • 2D speckle tracking used for radial (SDTrepsilon) and longitudinal (SDTlepsilon) systolic synchrony.

Main Results:

  • Established normal ranges for SDTs, SDTe, SDTrepsilon, and SDTlepsilon.
  • SDTs was gender-specific and dependent on LV ejection fraction.
  • SDTe depended on isovolumic relaxation time and mean Em velocity.
  • Radial synchrony (SDTrepsilon) was independent of clinical/echocardiographic variables.
  • No correlation found between longitudinal and radial synchrony.

Conclusions:

  • Provides normal reference ranges for LV synchrony using Doppler and speckle tracking.
  • LV longitudinal synchrony is influenced by gender and global LV function.
  • 2D speckle-derived radial synchrony is independent of clinical factors but has higher variability.
  • Longitudinal and radial synchrony are distinct and do not correlate.
Abstract

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