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Updated: Jul 4, 2026
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Immunofluorescence to Monitor the Cellular Uptake of Human Lactoferrin and its Associated Antiviral Activity Against the Hepatitis C Virus
Published on: October 1, 2015
Antimicrobial properties of lactoferrin.
Håvard Jenssen1, Robert E W Hancock
1Centre for Microbial Diseases and Immunity Research, #232 - 2259 Lower Mall Research Station, University of British Columbia, Vancouver, British Columbia, V6T 1Z4, Canada.
Biochimie
|June 25, 2008
Summary
Lactoferrin, a milk protein, exhibits significant antimicrobial properties. This review highlights its antibacterial and antiviral effects, crucial for host defense, especially in infants.
Area of Science:
- Biochemistry
- Immunology
- Microbiology
Background:
- Milk is a key nutritional source for mammalian offspring.
- Lactoferrin, a multifunctional milk protein, is recognized for its iron-binding capacity.
- Iron-binding by lactoferrin underpins its discovered antibacterial activity.
Purpose of the Study:
- To review the antimicrobial activities of lactoferrin.
- To emphasize the antibacterial and antiviral properties of lactoferrin.
- To discuss the antifungal and antiparasitic activities of lactoferrin.
Main Methods:
- Literature review focusing on lactoferrin's antimicrobial functions.
- Analysis of studies investigating antibacterial, antiviral, antifungal, and antiparasitic activities.
- Examination of lactoferrin's role in host defense mechanisms.
Main Results:
- Lactoferrin demonstrates broad-spectrum antimicrobial activity.
- Potent antibacterial and antiviral effects are well-documented.
- Antifungal and antiparasitic activities are also observed.
- Lactoferrin is an important host defense molecule, particularly during infant development.
Conclusions:
- Lactoferrin possesses diverse and potent antimicrobial properties.
- Its role in host defense warrants further investigation.
- Lactoferrin represents a promising natural compound for therapeutic applications.
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