Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evidence-informed evidence-making.

Kalipso Chalkidou1, Tom Walley, Anthony Culyer

  • 1Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. kalipso.chalkidou@nice.org.uk

Journal of Health Services Research & Policy
|June 25, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcriptome-wide mapping reveals an RNA-dependent mechanism of platinum cancer drugs.

bioRxiv : the preprint server for biology·2026
Same author

No shortcuts to universal health coverage: lessons from accountability initiatives.

BMJ global health·2025
Same author

Navigating health financing cliffs: a new era in global health.

Lancet (London, England)·2025
Same author

Allosteric modulation of protein kinase A in individuals affected by NLPD-PKA, a neurodegenerative disease in which the PRKAR1B L50R variant is expressed.

The FEBS journal·2025
Same author

Gender bias in health financing methods: metrics and data.

BMJ global health·2025
Same author

Harnessing health technology assessment in India: paving the way for sustainable healthcare solutions in developing countries.

BMJ evidence-based medicine·2025
Same journal

Patient reported outcomes of home diagnostics with colon capsule endoscopy - results from the 5G-SUCCEEDS study.

Journal of health services research & policy·2026
Same journal

Cost-effectiveness of synchronous telehealth versus face-to-face care for asthma management: A systematic review.

Journal of health services research & policy·2026
Same journal

Facilitators and barriers to implementing new models of care for patients in a rehabilitation care setting: A systematic review.

Journal of health services research & policy·2026
Same journal

Rapid adaptation of first contact physiotherapy services for musculoskeletal patients in the UK and Australia during the COVID-19 pandemic: A multiple case study.

Journal of health services research & policy·2026
Same journal

Moving toward integrated care for perinatal opioid use disorder and mental health in an urban safety-net hospital: A formative implementation evaluation.

Journal of health services research & policy·2026
Same journal

Beyond mitigation: Adaptation, policy and resilience for health services facing climate change.

Journal of health services research & policy·2026
See all related articles

Improving public health guidance requires addressing evidence gaps. Collaboration between the National Institute for Health and Clinical Excellence (NICE) and research funders can enhance the evidence base for better National Health Service (NHS) recommendations.

Area of Science:

  • Health Services Research
  • Clinical Practice Guidelines
  • Public Health Policy

Background:

  • National Institute for Health and Clinical Excellence (NICE) guidance quality relies on evidence.
  • Existing links facilitate evidence synthesis but not new study commissioning.
  • Knowledge gaps in NICE guidance development are not effectively addressed by new research.

Purpose of the Study:

  • Advocate for a publicly funded research agenda to fill NICE-identified knowledge gaps.
  • Describe collaborative efforts between NICE and the National Institute for Health Research (NIHR).
  • Propose enhanced collaboration between NICE and research funders to strengthen the evidence base.

Main Methods:

  • Discussion of current mechanisms for evidence synthesis and gap identification.

Related Experiment Videos

  • Review of early experiences between NICE and NIHR in research commissioning.
  • Proposal of strategies for improved NICE-research funder partnerships.

    • Main Results:

    • Limited pathways exist for translating NICE-identified evidence gaps into commissioned research.
    • Early NICE-NIHR collaboration demonstrates potential for research commissioning.
    • Enhanced collaboration can improve the evidence underpinning NICE recommendations.

    Conclusions:

    • A dedicated research agenda is crucial for NICE to address knowledge gaps.
    • Strengthening NICE's collaboration with research funders is vital for evidence-based guidance.
    • Improved evidence base will enhance the quality and efficiency of NHS and public sector services.