Angina at 1 year after myocardial infarction: prevalence and associated findings

Thomas M Maddox1, Kimberly J Reid, John A Spertus

  • 1Cardiology Section (111B), Denver Veterans Affairs MedicalCenter, 1055 Clermont St, Denver, CO 80209, USA. thomas.maddox@va.gov

Insights

Angina affects nearly 20% of patients one year after myocardial infarction (MI). Modifiable factors like continued smoking and depression increase the risk of post-MI angina.

Area of Science:

  • Cardiology
  • Clinical Medicine
  • Public Health

Background:

  • Angina management is crucial post-myocardial infarction (MI).
  • Prevalence and predictors of one-year post-MI angina remain largely unknown.
  • Understanding these factors is key to improving patient outcomes.

Purpose of the Study:

  • To determine the prevalence of angina one year after myocardial infarction (MI).
  • To identify sociodemographic, clinical, and treatment-related factors associated with one-year post-MI angina.

Main Methods:

  • A multicenter cohort study involving 2498 patients hospitalized for acute MI.
  • Angina assessment using the Seattle Angina Questionnaire one year post-MI.
  • Multivariate regression analysis to identify associated factors.

Main Results:

  • 19.9% of patients reported angina one year post-MI.
  • Younger age, nonwhite male sex, prior angina, prior coronary artery bypass graft (CABG) surgery, and recurrent rest angina during hospitalization were associated with one-year angina.
  • Continued smoking, post-discharge revascularization (PCI or CABG), and significant depressive symptoms (new, persistent, or transient) were also associated with one-year angina.

Conclusions:

  • Angina is prevalent one year after myocardial infarction, affecting nearly one in five patients.
  • Key modifiable factors associated with one-year angina include persistent smoking and depressive symptoms.
  • These findings highlight potential targets for intervention to improve long-term angina management post-MI.
Abstract

Related Concept Videos

Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
Angina V: Nursing Management01:20

Angina V: Nursing Management

Angina, a symptom of myocardial ischemia, requires a structured nursing management approach to ensure effective care and prevent complications like myocardial infarction. Comprehensive nursing care involves assessing, diagnosing, planning, implementing interventions, and evaluating outcomes, all tailored to the individual patient's needs.Patient AssessmentNursing assessment begins with a detailed subjective evaluation of symptoms, which typically include chest pain or pressure radiating to the...
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
Angina I: Introduction01:30

Angina I: Introduction

Definition and Symptoms: Angina (angina pectoris) is chest pain or discomfort caused by myocardial ischemia, which occurs when the heart muscle receives insufficient oxygen-rich blood. It typically manifests as pressing, squeezing, or crushing sensations in the chest and may radiate to the shoulders, arms, neck, jaw, or back.Primary Cause: In a healthy state, the coronary arteries can dilate (widen) to increase blood flow and meet the increased oxygen demand during physical activity or...
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...