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Choriocarcinoma in an AIDS patient--relapsing but not fatal
Archan M Shah1, Mark Tidswell, Michel Prefontaine
1Department of Medicine, Baystate Medical Center, Tufts University School of Medicine, 759 Chestnut Street - S2570, Springfield, MA 01199, USA. shaharch@yahoo.com
Abstract:
Choriocarcinoma is associated with high mortality in immunocompromised patients, in contrast to a good prognosis in immunocompetent individuals. Respiratory failure due to metatstatic choriocarcinoma is associated with high mortality in any patient. We report a case of a woman with AIDS that survived metastatic choriocarcinoma and respiratory failure. We also observed that in contrast to some in vitro studies, the markedly elevated levels of beta-subunit of human chorionic gonadotropin in this patient did not have any apparent inhibitory effect on viral replication.
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