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Hormone replacement therapy for the adolescent patient
Amy D DiVasta1, Catherine M Gordon
1Division of Adolescent Medicine, Children's Hospital Boston, 333 Longwood Avenue, Boston, MA 02115, USA. amy.divasta@childrens.harvard.edu
Annals of the New York Academy of Sciences
|June 25, 2008
Summary
Hormone replacement therapy (HRT) aims to mimic natural puberty in adolescents. This review guides clinicians on HRT
Area of Science:
- Pediatric Endocrinology
- Adolescent Medicine
- Reproductive Health
Background:
- Pubertal induction and hormone replacement therapy (HRT) in adolescents aim to replicate normal pubertal development.
- Optimal HRT regimens for adolescents require careful consideration of individual patient needs.
Purpose of the Study:
- To review current evidence on HRT for adolescent girls and young women.
- To guide clinicians in selecting appropriate HRT forms, dosages, and durations.
- To discuss benefits, risks, and special considerations in adolescent HRT.
Main Methods:
- Literature review of existing studies and clinical data on adolescent HRT.
- Analysis of goals, phases, and medication regimens for HRT.
- Examination of associated benefits, risks, and specific concerns.
Main Results:
- Limited data exist for optimal HRT regimens in adolescents.
- Commonly used HRT medication regimens are presented.
- Benefits and risks of various HRT methods are discussed.
Conclusions:
- HRT in adolescents requires individualized treatment plans.
- Clinicians must weigh benefits against risks, considering factors like eating disorders and bone health.
- Further research is needed to establish optimal HRT protocols for this population.
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