Related Experiment Video
Updated: Jul 4, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
Acute pyelonephritis caused by Aerococcus urinae in a 12-year-old boy
Thomas S Murray1, Kenneth L Muldrew, Robert Finkelstein
1Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA. Thomas.s.murray@yale.edu
Insights
Aerococcus urinae can cause kidney infections, even in children. This case highlights the importance of considering this bacteria in pediatric pyelonephritis, especially in those with urinary tract abnormalities.
Area of Science:
- Microbiology
- Pediatric Nephrology
- Infectious Diseases
Background:
- Aerococcus urinae is a Gram-positive coccus.
- It is known to cause urinary tract infections (UTIs) in adults with genitourinary (GU) disease.
Observation:
- A case of pyelonephritis caused by A. urinae in a 12-year-old boy is presented.
- The patient had a history of pyeloplasty and GU reflux.
Findings:
- This case demonstrates A. urinae as a causative agent of pyelonephritis in a pediatric patient.
- The infection occurred in a child with pre-existing GU tract abnormalities.
Implications:
- Highlights the potential for A. urinae to cause severe UTIs in pediatric populations.
- Suggests considering A. urinae in the differential diagnosis of pyelonephritis in children with GU anomalies.
- Emphasizes the need for further research into A. urinae infections in children.
Abstract:
Aerococcus urinae are Gram-positive cocci that cause urinary tract infections in adults with underlying genitourinary (GU) tract disease. We report a case of pyelonephritis caused by A. urinae in a 12-year-old boy with a history of pyeloplasty and GU reflux.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Pyelonephritis I: Introduction
Urinary Tract Infection II: Pathophysiology
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Urinary Tract Infection I: Introduction
Urine Studies II: Urine Culture and Sensitivity Test

