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Updated: Jul 4, 2026

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
Published on: December 15, 2023
[Relativity analysis of chronic hepatitis B virus genotype and clinical pathology]
Wei-ping He1, Jin-hua Hu, Hui-fen Wang
1The Liver Failure Therapy and Research Centre, No. 302 Hospital of the People's Liberation Army, Beijing, China.
Objective:
To explore the relationship between chronic hepatitis B virus genotypes and clinical pathology.
Methods:
HBV genotype was determined in 92 cases with chronic hepatitis B patients and the relationship between HBV genotypes and clinical, serological and histological data of the patients was analyzed.
Results:
Sixteen cases were infected with HBV genotype B (17.4%), 71 with genotype C (77.2%), 3 with HBV classified as genotype B+C (3.2%) and in 2 (2.2%) cases HBV genotype was not confirmed. ALT level and HBV DNA load log value were (82.6+/-82) U/L, (84.7+/-71.5) U/L and (5.8+/-1.4), (5.9+/-1.5) respectively in genotypes B and C patients, in 8 cases of genotype C group liver cirrhosis was diagnosed, but no statistical significance was seen.
Conclusion:
No significant differences in clinical, serological or histological data were detected between genotypes B and C patients.
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