Related Experiment Video
Updated: Jul 4, 2026

Metabolic Profiling to Determine Bactericidal or Bacteriostatic Effects of New Natural Products using Isothermal Microcalorimetry
Published on: October 29, 2020
Mycobacterium peregrinum: bactericidal activity of antibiotics alone and in combination
Ana Santos1, Rosa Cremades, Juan Carlos Rodriguez
1Section of Microbiology, Hospital General Universitario, E-03203 Elche, and Universidad Miguel Hernandez, Elche, Spain.
Abstract:
Mycobacterium peregrinum is a rapidly growing mycobacterium that is occasionally associated with disease at different locations. At present, little information is available on antibiotic activity against this microorganism. For this reason, we have carried out a study on the in vitro activity of 15 antibiotics, alone and in combination, against M. peregrinum. Our study shows that the new fluoroquinolones with a C8-methoxy group, especially moxifloxacin, exhibit greater activity against this species. These data should be evaluated in clinical assays or animal models in order to confirm their clinical significance.
Related Concept Videos
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Clinical Significance of Antibiotic Resistance
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Inhibitors of Gram-positive Cell Wall Synthesis
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

